my company wants to pay us quarterly versus monthly for commission. Will I pay more taxes this way? say $3300 per month versus $10,000 per quarter. Base pay $95,000

not really; say, your commission is paid monthly/quarterly/annually then you will pay taxes at a supplement rate. IRS guidelines require employers to withhold tax at a 25% rate on top of withholdings for social security and medicare taxe in general, If your income is generated from commission and base pay then it might be a good idea to adjust your tax withholding on your W4. If you find you?re receiving big tax refunds on your return, then you can have less tax withheld from your W4. Before changing your withholdings you might want to discuss with a tax pro,i..e., IRS Enrolled Agent or CPA in your local area for accurate help